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Using two separate drugs to lose weight naturally can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you should err to the side of caution and allow the FDA do its job and demand some study be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on their own medications. Researchers found out that participants using this drug to get a year, dropped a few pounds within 4 weeks and have kept the weight off through the entire 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them more effective and safer. Combo-pilling could be the newest fad or also the newest ahead under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills has become popular could be the fact that by right now there aren't long term prescription diet pills that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartbeat, and mustn't be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure level and heartrate and must not be used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. 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